PubMed COVID-19 Clinical Care
38761 - 38770 of 60077 results found
Patch-clamp studies and cell viability assays suggest a distinct site for viroporin inhibitors on the E protein of SARS-CoV-2
Description
CONCLUSIONS: This study demonstrates direct inhibition of the SARS-CoV-2 E protein by classical viroporin inhibitors. Ivermectin and milbemycin inhibit the E protein channel but their cytotoxicity argues against clinical application.
Rapid screening of SARS-CoV-2 variants, a key tool for pandemic surveillance
Description
The utility of reverse transcription-polymerase chain reaction (RT-PCR) in analysis SARS-COV-2 variants was evaluated. RT-PCR tests were used to analyse the majority of new SARS-CoV-2 cases (n = 9315) in a tertiary hospital (Madrid, Spain) throughout
SARS-CoV-2 inhibitory activity of a short peptide derived from internal fusion peptide of S2 subunit of spike glycoprotein
Description
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has posed a great concern in human population. To fight coronavirus emergence, we have dissected the conserved amino acid region of the internal fusion peptide in the S2 subunit of Spike
The importance of getting the ethics right in a pandemic treaty
Description
The COVID-19 pandemic revealed numerous weaknesses in pandemic preparedness and response, including underfunding, inadequate surveillance, and inequitable distribution of countermeasures. To overcome these weaknesses for future pandemics, WHO
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning
Description
Federated Learning (FL) is an emerging distributed learning paradigm which offers data privacy to contributing nodes in the collaborating environment. By exploiting the Individual datasets of different hospitals in FL setting could be used to develop