PubMed COVID-19 Clinical Care
52521 - 52530 of 60077 results found
Severe COVID-19 is associated with molecular signatures of aging in the human brain
Description
As coronavirus disease 2019 (COVID-19) and aging are both accompanied by cognitive decline, we hypothesized that COVID-19 might lead to molecular signatures similar to aging. We performed whole-transcriptome analysis of the frontal cortex, a critical
Older adults across the globe exhibit increased prosocial behavior but also greater in-group preferences
Description
Population aging is a global phenomenon with substantial implications across society^(1,2). Prosocial behaviors-actions that benefit others-promote mental and physical health across the lifespan^(3,4) and can save lives during the COVID-19 pandemic
Blocking eicosanoid signalling prevents severe COVID-19
Description
No abstract
SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response
Description
Reports of post-acute COVID-19 syndrome, in which the inflammatory response persists even after SARS-CoV-2 has disappeared, are increasing¹, but the underlying mechanisms of post-acute COVID-19 syndrome remain unknown. Here, we show that SARS-CoV-2
A longitudinal analysis of the impact of the COVID-19 pandemic on the mental health of middle-aged and older adults from the Canadian Longitudinal Study on Aging
Description
The coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented challenge to public health, with over 233 million confirmed cases and over 4.6 million deaths globally as of September 2021¹. Although many studies have reported worse mental
MasitinibL shows promise as a drug-like analog of masitinib that elicits comparable SARS-Cov-2 3CLpro inhibition with low kinase preference
Description
SARS-CoV-2 infection has led to several million deaths worldwide and ravaged the economies of many countries. Hence, developing therapeutics against SARS-CoV-2 remains a core priority in the fight against COVID-19. Most of the drugs that have
People affected by dementia had mixed experiences of using technology during COVID-19
Description
No abstract
Molecular characterization of Candida auris outbreak isolates in Qatar from COVID-19 patients reveals the emergence of isolates resistant to three classes of antifungal drugs
Description
CONCLUSION: C. auris isolates from COVID-19 patients, and from most non-covid patient samples in Qatar were highly clonal. The data demonstrated the emergence of multidrug-resistant strains that carry novel mutations linked to enhanced resistance to
Prospective cohort of COVID-19 patients requiring hospital admission in Douala, Cameroon
Description
CONCLUSIONS: Despite the lack of invasive mechanical ventilation, 76% of COVID-19 patients survived.