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PubMed COVID-19 Clinical Care

17111 - 17120 of 60077 results found

Colloidal aggregation confounds cell-based Covid-19 antiviral screens

Date
Tuesday, November 14, 2023 - 4:00 AM
Description
Colloidal aggregation is one of the largest contributors to false-positives in early drug discovery and chemical biology. Much work has focused on its impact on pure-protein screens; here we consider aggregations role in cell-based infectivity assays

Increased Levels of Galectin-3 in Critical COVID-19

Date
Tuesday, November 14, 2023 - 4:00 AM
Description
Severe COVID-19 is related to hyperinflammation and multiple organ injury, including respiratory failure, thus requiring intensive care unit (ICU) admission. Galectin-3, a carbohydrate-binding protein exhibiting pleiotropic effects, has been